Different Subtypes of Osteosarcoma: Histopathological Patterns and Clinical Behaviour

Osteosarcoma (OS) is a primary malignant bone tumour that usually occurs in children and adolescents. OS highly aggressive type with propensity for local invasion systemic early metastasis to the lungs or other bones. According World Health Organization, there are different subtypes of OS, including conventional (osteoblastic, chondroblastic, fibroblastic), telangiectatic low-grade small-cell parosteal periosteal high-grade surface OS. In this mini review, we will discuss background histopathological patterns clinical behaviour disease. Understanding their pathogenesis crucial developing more precise effective therapies patients.